Description:
This advanced intermediate-level course focuses on the role of molecular docking in vaccine design. Learners will explore the process of docking antigens to immune receptors (e.g., MHC I, MHC II), evaluating protein folding, and ensuring the stability of the designed vaccines. The course also covers the use of MOE, Schrödinger Desmond, and AutoDock Vina for vaccine structure optimization and molecular docking. By the end of the course, students will have the skills to design and model subunit vaccines and predict antigen-receptor interactions.
Learning Outcomes:
By the end of this course, learners will be able to:
Perform molecular docking of antigens to immune receptors using MOE and Schrödinger Desmond.
Evaluate protein folding and stability of designed vaccines.
Design subunit vaccines using computational tools and predict their interactions with the immune system.
Utilize molecular databases and immunoinformatics tools to improve vaccine efficacy and accuracy.